Metoprolol Succinate Extended Release & Clindipine Tablets – Nedline M 10/25 Tablets

NEDLINE M 10/25 Tablets – Dual Action for Hypertension and Heart Protection.

NEDLINE M 10/25 Tablets – The dual combination of Metoprolol Succinate Extended Release & Cilnidipine Tablets provides effective blood pressure control and cardiovascular protection:

Metoprolol – A selective beta blocker with the primary function to manage high blood pressure (hypertension), high heart rate (tachycardia), and cardiovascular events.
It commonly works by selectively blocking beta-1 adrenergic receptors, which reduces the effect of epinephrine (adrenaline) and non-adrenaline, resulting in negative inotropic (decreased heart rate) and negative chronotropic effects (decreased force of contraction).
It also helps to control the sympathetic nervous system, which helps in conditions like tachycardia.

Cilnidipine – A calcium channel blocker (CCB) that belongs to the dihydropyridine class, primarily used to manage high blood pressure (hypertension). It works on both L-type and N-type calcium channels and their blockage results in relaxing blood vessels and lowering blood pressure. Its dual action on calcium channels offers broader therapeutic benefits compared to conventional calcium channel blockers.

Key Benefits of Metoprolol Succinate & Cilnidipine Tablets – NEDLINE M 10/25 Tablets
✅ Synergistic Blood Pressure Control – Combination works through two complementary mechanisms—relaxing blood vessels and managing high blood pressure and tachycardia via dual calcium channel inhibition and beta receptor blockade.
✅ Enhanced Efficacy Compared to Monotherapy – Unlike other calcium channel blockers or cilnidipine alone, this combination with metoprolol reduces reflex tachycardia, a common side effect of vasodilators, making it ideal for patients with tachycardia and arrhythmias.
✅ Cardioprotective Benefits with Long-Term Safety – This combination offers cardioprotective effects while minimizing respiratory side effects, ensuring a favorable safety profile for long-term use.

Recommended By Specialists:
👨‍⚕️ Cardiologists: Prescribed to manage hypertension, tachycardia, and certain types of arrhythmias, providing both blood pressure control and heart rate management.
👨‍⚕️ General Physicians: Used for patients with high blood pressure, especially when monotherapy is insufficient or when there is a need to control heart rate alongside hypertension.

INDICATIONS:
✅ Angina
✅ Sympathetically driven hypotension
✅ Management of tachycardia and arrhythmia